After 4 months we are finally nearing the end of our dietary journey. We discussed the basic context of Macronutrients (protein, carbohydrate, and fat) as “fuel.” We learned that there is a group of Micronutrients – vitamins, minerals and phytochemicals that all constitute “service” or biological maintenance. We understand that fat has more energy density (2x) than protein or carbohydrate.
Our body uses primary fuel glucose/glycogen through the TCA or krebs cycle to obtain energy (brain biggest single user, followed closely by liver and muscle) and the body stores a glycogen (a special muscle protein with a carbohydrate shell) and fat (adipose tissue) for rainy day “reserves.”
If you are REALLY starving, or consume an excess, protein is (inefficiently) converted to be used in the sugar cycle through gluconeogenesis (creating new glucose from protein). The body protects protein a bit, because there’s no sense in digesting the muscle tissue when there is plenty of fat or glycogen around to tap into. Fat on the other hand goes through a different pathway from protein/carbohydrate to derive energy (beta oxidation), but after that are dumped into the same krebs cycle.
Proteins DO NOT = Flesh. There are many very important proteins from enzymes like insulin to blood proteins like hemoglobin, which are recycled and recreated every day. Proteins are macromolecules, unique sequences of amino acids that are defined by our genes. New proteins are created every second in your body and others are eliminated. Protein is NOT a food group that you need to “manage.”
You should now recognize that when we break down the bonds of a starch (a carbohydrate) into glucose (a simple sugar) it happens through an enzyme (e.g. amylase created by the AMY1 gene) and we don’t have the enzyme to break down fiber (cellulose). Remember that both starch and cellulose are long chains of glucose – only one is digestible by Humans. Termites and cows eat cellulose in wood and grass to obtain glucose. Similarly, agave and corn syrups are both high fructose (a 5 carbon sugar) syrups and one is squeezed from corn, the other from Agave plants. Fructose is fructose and I’m not a big fan of simple sugars of any kind as a main dietary source of energy.
We discussed fat as a storage container for energy and it’s necessary role in the diet. We touched on cholesterol – the bold blood biomarker advertised as an indicator of health – and its role as a basis for Vitamin D and all cell walls. We know that to lose weight we MUST go on a naturally high-fat diet (consuming our own).
Finally we figured out that proteins have a bit of an identity crisis in that they CAN be digested for energy, but what we actually need from them is the 10 essential (indispensable) amino acids that our body can’t synthesize. This causes the protein conundrum and is what sends everyone into a “pass the protein” muscle-head mindset. Ultimately our body needs energy and amino acids to repair or build muscle that has been biologically stressed from a workout. “Protein” does not have to be the source of both the energy and the amino acid. It’s only required for half of the 20 amino acids (the 10 essential/indispensable).
To be clear about our need for amino acids, I want to dig deep, to the very OTHER end of this dialog, because it will be far easier for you to let go and follow along. So please, set aside your bias and what you may believe about “protein” and let’s look at it from a very different perspective.
Roots
Let’s take a trip back to grammar school science class. The plants use chlorophyll and CO2 (carbon dioxide) along with energy from the sun for photosynthesis (photo – light + synthesis – putting together) . Plants make sugars – sugar cane? Fruits? Tubers/rice starches (poly sugar)? All from carbon dioxide and sunlight. When you see the giant redwoods in California we KNOW they didn’t eat anything at all to grow that big. they absorbed a little carbon dioxide (okay a LOT) from the air, sprinkled sunshine, and presto.
These are MASSIVE living organisms with complex biochemistry and structure. They are full of all sorts of regulatory proteins and cells. Trees create cellulose (remember – long chains of glucose with beta amylase bond) to reach enormous heights. How about all the chlorophyll protein in the leaves? More massive and more protein in one of these single trees than your biggest meat-head on Venice Beach – don’t you think? In fact, did you know scientist are devising new ways to classify trees based on Phylogenic analysis – looking at molecular structures of DNA, RNA and protein to group closely related organisms (like trees)?
Where do they get the protein?
The roots. They form these amino acids (remember Nitrogen?) from the “fertilizer” we put on the ground around them. Farmers often refer to the fertilizer as nitrogen or nitrates and while there are a few more things they get, understand that the nitrogen is critical for both protein and DNA/RNA. They need these same building blocks, but can’t seem to get the “perfect protein” of an egg into their system.
Guess what – Plants can synthesize ALL 20 amino acids. A potato has every single amino acid. So does rice, but wait, aren’t these “carbs?” Not only that, you’ll remain in POSITIVE nitrogen balance even if that’s all you eat [Nitrogen Balance is a measure excreted excess nitrogen from protein not needed in urine/feces]. I’m not suggesting an all potato diet, but if this is true, how does that impact how you think about food?
Where do you get your protein?
Even venus flytraps and other carnivorous plants derive some of their nitrogen from fertilizer and ALL of their energy from the sun. They shun protein as a fuel.
The nitrogen cycle is well known and there’s no need to go into in in great detail, but just understand we can eat animals that eat plants or we can eat plants. We can get complete, sufficient compliment of the 10 amino acids that we don’t make either way. There’s no debate. Everything else is simply ideological arguments and I gave up politics when I retired from my government job. Everyone can debate it, but the science isn’t going to change.
Tie Me Dinosaur Down, Sport.
Herbivores eat plants (maybe not redwoods) and they get essential amino acids and energy from grasses, leaves, and even fruits. We are talking about some of the largest animals on the planet and even herbivore dinosaurs out numbered carnivorous dinosaurs. We have discussed that a “grass fed” cow that has “complete protein” (amino acid profile) and gets its protein from…grass. If we ingest the beef, we get the amino acids (synthesized by the plants) use some for repair and burn the rest. We don’t store amino acids, we just use them.

Potato - Vitamins, minerals and protein - OH MY! There are many foods with protein that we unwisely categorize by the dominant macronutrient (e.g. potato = carbohydrate). This is a mistake. source: http://www.potato2008.org/
I would have to say my “beef” with all the protein double-talk is that it’s not hard to understand. Why do we complicated it? Why don’t we talk about foods to eat instead of vilifying/praising the macronutrient de jour. I don’t want to convert anyone and I don’t want to be converted. I just want to understand a pattern of eating and how it fits in with basic caloric and nutrient needs.
This is really not difficult science and yet everyone pauses at a vegetarian or vegan diet with an incredulous question, “where do you get your protein?” By now, hopefully that is sounding pretty ridiculous to everyone. It’s not difficult to eat complete amino acid profiles or sufficient quantities. You don’t have to mix and match sources. The fact is that we are flooded with a massive excess of protein/amino acids every day and most of them are inefficiently burned as fuel putting loads on our other organs to screen, sift and sort.
This is NOT an appeal to get you to “switch” a diet. It’s simply a basis for a rational understanding of what you eat and why. It’s a foundation of information and review of things we know to be true so that you may then ask yourself a basic question: why would anyone educated to any advanced level be recommending or suggesting that “protein” is a necessary “something” you actually have to manage day to day?
This kind of thinking isn’t limited to protein pandering by diet gurus, physicians, and nutritionists. Remember, the sun once rose in the east and set in the west and that was PROOF that the sun revolved around the Earth – can’t you see it right there every day, you idiot? So democracy doesn’t win in science, at least not for long.
This protein argument is not much different and it’s most likely rooted in economy of agriculture, ideology, and cultural bias. I can’t believe how I have been attacked for just EXPERIMENTING with a vegan diet. It’s a “label” – oh, so you are a VEGAN? NO, I am not a vegan. No one should have to bow to such social labels, but we all know it happens on all sides of the debates.
I don’t want to engage in this debate of a pragmatic vegetarian (for health) vs an ideologic vegetarian (don’t eat animals), because it has all sorts of dimension, but none of the debate needs to be about protein, carbohydrates or fats. Food doesn’t need to be described that way and everyone seems to have an ideology that drives their view of the science, rather then letting the data speak for itself.
If you want to deal in ideologic vegetarian arguments, I heard the most persuasive argument against eating animals (carnism) in my life recently by Dr. Melanie Joy and she does make some good points. I wan’t persuaded for those reasons, but it was the most compelling argument I’ve heard to date. This is not my mission, but then again, I don’t see the difference between eating your house cat, a salmon or a cow in terms of basic food macronutrients. They would all provide fat/amino acids with a few fat soluble vitamins from a strictly scientific perspective. When you pause to think about it, other than fish and perhaps the seals eaten by Inuitsboost meat consumed is from herbivoires. Generally speaking, we don’t farm carnivores and I think for good reason. These are all available from plants as well. These are not mutually exclusive arguments.
I’m not advocating eating cats or avacados right now, just making a point. We all have some sort of ideology that is brought to the table to justify what we do and reject what we “believe” is wrong. Kathy Freston (the veganist) talks about “leaning into” a vegan diet in her new book, The Lean. Her husband eats meat. She does not, but she can tell you all sorts of reasons (like her personal ideology and ridding herself of life-long acne). She and I have discussed this and we both have to laugh, because her book or cause isn’t a discussion about protein.
On the other side of the table, there are many “Vegans” that parade unproven health benefits to disguise ideological arguments. That is no more correct than the USDA misrepresenting food calories (like fat) on labels using a ridiculous per weight reporting system combined with recommended daily values of nutrients described per calorie. Of the two issues (vegan health or food labels), the latter is probably more responsible for deleterious health of the world.
So, to everyone reading – I am openly experimenting (with good results) with a nutrient dense, calorically restricted diet and I have been working on limiting protein consumption and biosimilar macromolecules by eating a vegan diet. I get plenty of protein.
I needed to understand how to burn fat quickly and eventually it challenged everything I knew about food. I learned that when you cut down to a “naturally high-fat diet” of love handles, beer bellies and thunder thighs, it’s amazing how well it goes. Sprinkle a little micronutrient on there and get your game on. Adding thermal loading takes it to an entirely different level.
Got Milk?
Finally, how much amino acid (protein) do we need? I decided to do a little research to look at protein, carbohydrate and fats in various milks. I mean, would anyone argue that a growing baby isn’t best fed by its mother’s milk for at least some period of life? This is not by any means the final word, but it certainly might give us some clues; although sometimes I feel like I’m living in the nutritional equivalent of National Treasure. I found sources everywhere and put them into a giant spreadsheet so I could plot protein, lactose (carbohydrate), and fat.
I won’t do a lot of interpretation, but instead let you take a look. How do Human infants stack up to other species? We learned last year (BATgirl 1 & 2) that human infants are born with more fat and BAT than nearly any other species. We know that there are many factors in determining the “perfect food,” but one would think that good ole Mother Nature might get something right. So how does it look?
[Click to Enlarge]
I think right away you should recognize species of arctic or aquatic environments as having a lot of energy and “leaning” on fat (sorry Kathy, damn that’s a good term). Then there are the fast growers, like rats, that have enormously high protein requirements. I haven’t plotted some of the other things I have in the table like “time to sexual maturity” (do men ever get there?), but there is a lot to learn.
Also, I’m not suggesting that this is the holy grail of diets – you all know that I believe balancing protein, carbohydrates and fats is not only futile, but is exactly how we created this entire mess in the first place. I just want to point out a few obvious confused facts in the diet lore that abounds. Is goat milk REALLY a closer to Human milk than cow milk? I’ve heard that before. What species matches ours most closely and if we are to consume milk past weaning, why don’t we drink THAT? Am I sounding like an Ass? Wait, what about the fat?
Marketing is way ahead of knowledge and I too stayed in the dark for WAY too long.
We are basically starchivoires. It’s how we derived our calorie needs for millennium and it really helped us evolve this tremendously energy-hungry brain. Underground storage organs, Tubers, corms, rhizomes, and bulbs, are available year round in the areas where Humans are shown to evolve (my ancestors: maternal – Haplogroup J1b and Paternal – Haplogroup R1b1b2a1a2 as I had my genotype analyzed along the way). With that said, we can eat other things too and they may prove to be better in the long run, but starches are not “evil” and I’ve seen direct proof of diabetes reversal on a starch-based diet.
I think you’ll see the work of Dr Nathaniel Dominy move ahead of Dr. Loren Cordain in the future and yet both have something to important to contribute to evolutionary biology foundation. I have absolutely no doubt that meat has played a significant role in our evolutionary past and feel equally certain that excessive dairy consumption has been part of the energetic demise.
Many Paleo and Vegan proponents agree on the deleterious health effects of milk, but is it the protein, carbohydrate, or fat that’s the reason? What about other biomimetics (biosimilar compounds) in dairy (let’s lump cheese, yogurt, ice-cream in while we ware whipping) and what role do they play? Is it an immune response to whey are casein that is similar as the oh-so-popular evil wheat-gluten protein? We just aren’t sure and yet there are THOUSANDS of good, peer-reviewed papers on the negative effects of dairy consumption and none of it ends up on the “got milk” posters in the school cafeterias.
We know, for example, that bovine (cow) insulin is only different by three amino acids (out of 51) from human insulin. If you believe that human infants get very important enzymes and protective hormones from ingesting their mother’s breast milk, can you at the same time reject that you might be getting harmful ones by drinking the milk of another species decades after you would have been naturally weaned? What health impacts occur due to these biologically active compounds? What if we package it up as “solids” and feed it to our kids three times a day as cheese? Why is it so damn hard to walk away from eating it???
Did I mention how much I LOVE to eat cheese and yogurt? Well, I do and I still do even after not eating it regularly for nearly three years. I’m guilty, but I have that evolutionary big brain and I want to use it to inch my health along.
There are plenty of successful groups of people (like the inuits) that have moved into more energy demanding environments (like cold) and have been able to adapt the diet to eating higher levels of fat to make up energy deficits. The same is true of the original mediterranean studied in the late 50s (now the basis of the olive-oil craze). We can eat energy dense foods when we NEED the calories. Are they really more important?
I know that calories count. The discrepancy is in the counting and labeling.
I hope this has been informative. Again, the take home is that when we are trying to run a calorie deficit, don’t fall for all of the little tricks – you’ll have to get over the addiction to calories one way or another whether they originate as ingested carbohydrate or fat. No one knows for certain what the “real answer” will be, but I hope all of you feel a little more well-equiped and begin talking about FOOD not protein, carbohydrate or fats. What I’ve learned first hand through mild cold stress is that the Human body is amazingly adaptive. You can’t fool it easily and there’s no need to do it.
Note on comments – Let’s not diminish this to a vegan-paleo debate, nor talk about co-founding variables in the china study. What I am more interested in help is in the foundation of FOOD and food groups in lieu of protein, carbohydrate and fat. I want you to see that food is typically a mixture of two or all and that we end up in traps by the “majority macronutrient” classification scheme.
I will touch on the feed forward response, satiety and absorption next and then we’ll return to the regularly scheduled program on mild cold stress – already in progress. Thanks to EVERYONE for support (paypal) and acting so incredibly civilized. I think this blog is starting to take root over in the paleo and vegan worlds, let’s hope they all remain as respectful as everyone has here. I really appreciate it and apologize that we had to veer off mild cold stress for foundational material. It will be necessary information for the next step in thermal loading.
And last, but not least, having just spent a week with Wim Hof over at his home in Amsterdam planning our next chapter, take a few minutes to look at these hysterically funny commercials by Columbia Sportswear:
https://www.youtube.com/watch?v=17Pc85ypazEYou can see them all at: Columbia Sportswear Omini Heat
and let’s NOT forget our very own Andrew Stemler at Crossfit London:
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Thanks Ray! Awesome amino acids for thought, hehe!
Where did you get genotype analyzed?
Ray
You make a lot of sense.I am more convinced that you are right. A very thoughtful analysis if food and diet dogma.I am impressed and grateful for your work. I read Tim’s work on cold stress and I am very interested to learn more on the thermal loading.
Thanks
Neal
Thanks Neal
I still think there will be advantages to all the various “eating strategies” out there and I don’t claim to have the corner on eating. I just wanted to try to start moving us back to talking about food instead of trying to be bench-pressing biochemists. It really isn’t that complicated, but it sure would be better to have a good nutritional foundation.
Ray
Agreed…i like trying new stuff and experimenting actually. I will sign up for tracking shortly and post as I go along with a combination strategy 🙂
Fantastic!
Ray
How many more posts before we get to the actual practical application of the theory and specifics about what to eat, how much etc?
Easy for you to say in one sentence. LOL.
I want to separate the diet work from the thermal loading, because many have a “way of eating” that may be different than what I recommend. If I lay out this foundation, you guys will all see why these work (thermodynamically speaking) on your particular diet and then you can choose the route based on what you want to do. You won’t have to count protein and carbs any more.
Next post will be “Gut as an endocrine organ” where we’ll will touch on Metabolic Syndrome and microbiome and following that I’ll introduce The Food Triangle, which will open up the door for eating. From there, I have teamed up with a fantastic chef/cook/writer/photographer/mom in San Francisco and we’re going to spend a lot of time cooking and eating with those that want to join us on the other site.
I hope NEVER to talk about protein, carbohydrate or fat on that site at ALL. Much rather talk about ninja blenders and blanching. For those that love to cook, or never really learned, we are going to create fantastic food that’s not cluttered with calorie or super secret ingredients. It should work equally as well if you shop at Whole Foods or Walmart. Best part is that you can eat as MUCH as you want and you’ll be fine.
Did I tell you I love to eat?
Ray
Can’t wait for that site! Will you share it soon?
thanks Ray!
Yes…I have been working on it the last few weeks. Unlike this one, I will have a little help and since I cook nearly every day, much less time preparing. Don’t have to think about it much. I’ll have to sort through it a tad to figure out which recipes can apply to other diets, but that’s pretty easy..
Ray
Ray,
Rock on! I, for one, am looking forward to new recipes. Lately I’ve been following Yottom Ottolenghi out of London. His recipes might fit in well with what you are doing.
Thanks,
Ron
Thanks.
Will check it out and let you know when we’re ready to go. Recipes will be nutrient dense/paleo friendly for the most part. There will be a few that deviate one way or the other.
Ray
Ray,
Wow, my head hurts reading that stuff! lol! I was star-struck when I saw me standing in front of the redwood in the photo! Great info and hopefully once I read it a few more times, I’ll get at least some of it! Keep up the good work!
Your bud,
Vance
tis you by the tree! You had no idea I was thinking, “where in the hell did that tree get the protein?”
Thanks!
Ray
Ray
I have also been thinking about those who love to do juice fasts. The micronutrient density is high and now I realize that macronutrient content is also adequate as well. I don’t mind the juicing at times but i love the fullness of eating my vegetables and fruit actually..
Yes. I’ve spoken with joe cross quite a bit and we agree. Juicing (mostly vegetables) is just a way to get a nutrient dense diet with out “realizing it.” it’s sort if a hand holding fast as you get a ton of water, soluble fiber, and other micronutrients. Could you just eat the vegetables? Absolutely. You have to chew thoroughly and eat a large volume.
Certainly a pitcher of apple or orange juice is not what I’m suggesting.
Fasting or Alternate Day Fasting (ADF) is also more easily experienced or tested using juice to lean on. It helps with those addicted to calorie and withdraw. I think it can be overdone with fruits unless you’re going to extremes in training/diet, but it’s definitely something to experiment with.
Ray
Ray
Yes fruits can do that for sure. I am undertaking a 10-14 day juice fast( mostly green veges and a few berry type fruits) along with mild cold stress. I tropically do weight training 3 days a week and HIIT 2 days a week. So i will modify and see if I am able to stimulate a little more fat loss. I like your description of “high fat diet”. Will report back and let you know how that goes
Neal
Hi Ray,
I have just found your blog, and spent the past few days reading over your posts. You really made me think about things I already knew (how herbivores get their amino acids, etc) in a very different way.
Will you be doing a few posts on micronutrients? It seems hard to be able to get the recommended calcium intake on a vegan diet?
Keep up the good work,
Jerome
Thanks Jerome
Yes, but not at this detail, because we just don’t know. I’d say at best we know more is good when they come in quantities/ratios that are found in “real” food and perhaps all are bad when they come in pills. Perhaps….I don’t know.
I’ve not seen anything that suggest that as micronutrient density increases via food intake, health declines. Will we figure out all the bioactive phytochemicals? Perhaps – one day, but until then the easiest method is Fuhrman’s H = N/C.
Ray
HI Ray
I was reading through again and had a question. As body fat levels drop I was under the impression that sustained calorie restriction or fuel restriction can lead to a rise in cortisol etc and its possible our metabolic rates slows and that if we have more muscle relative to fat the body will pull from those muscle reserves. Hence the difficulty in getting really lean. However, I have also read that as long as you use the muscle it tends not to be utilized for fuel. Do you have any comments on this?
Neal
So it’s a good question. Also relavent is at what level of “5th avenue/Hollywood fitness” is really “primal’ or natural? We have bones, not bodies in fossil records. I’m willing to bet we over think a lot of this.
I’m in complete awe of the human body. Things I do in attempt to “trick it” into doing what I want are often foiled. I’ve witnessed first hand our science moving from gene deterministic (not our fault) to a symphony of complexity we’re attempting to nudge in the right direction.
Our goal in the 90s was to understand the lock and key world of the protein chemistry that controls every single biological process in one way or another. I think that if there was a single theme at the last TEDMED conference it was that molecular biology approach has largely failed. We will solve our issues before we understand them – not too different then science of the past. Science is ever evolving and can start one way and turn out completely different.
Metabolic syndrome is a syndrome of over consumption, not starvation. If metabolism falls, you eat less. In our studies on small mammals, worms and yeast, caloric restriction sets off a cascade of protective biological functions.
We’ll figure it out eventually. Until then there are tons of benefits to increasing nutrient density in your diet though cruciferous greens and other vegetables.
There is, unequivocally, no way for your body to stay (within
Thanks. Like your comment about the “bones not bodies” :). So true
Neal
Ray,
Have you found that your oral body temperature has raised, lowered, or remained constant after exposure to cold stress? And if it did change, for how long did the effect last?
Ideally, core temperatue shouldn’t change much and if anything go up slightly. Drops in core would indicate mild hypothermia and mean too aggressive of exposure – you don’t want your core temp to fall.
Wim’s core goes up to about .5 degrees when he does the world record attempts in ice. He has developed the ability to produce enourmous amounts of non-shivering heat.
Oral temps aren’t always accurate at this level and work better at normal body ranges. Rectal and swallowing a temp transmitter are probably best indicators.
Many report a “flush feeling” after exposures that lasts some time. It’s not a hot, uncomfortable feeling – just feels as if you radiate heat more effectively. It could be a skin sensory artifact (like I demonstrated in an earlier post).
Would like to hear your experience. There’s no wrong observations – only our occasional misinterpretations.
Thanks!
Ray
I wish I’d been taking my temp since before beginning cold exposure. After taking a couple days off from the cold I took my temp (on a cheap digital thermometer) and apparently it’s too low to read. Interesting. I tried again on a similar thermometer and got the same results. I’m going to get a standard thermometer and check again.
A quick search on the web found that calorie restriction (which I’ve been doing for about 6 weeks) may result in a lower body temp (http://bit.ly/GLRi2d) so If I’m low again I’ll hope that’s the cause since the alternative is not so hot. Pun intended.
After the cold my skin stings for a bit and I shiver occasionally but overall it’s not an unpleasant experience. I still wonder if wearing a hoodie and sweatpants is undoing all of my hard “work”. I look forward to learning some practical techniques, especially how to control my automatic response to cold water immersion.
Hi Ray, I was just wondering what the thermogenesis protocol you actually followed to achieve the fat loss in 4HB was, or if you’ve found something better now what you actually recommend doing. It seems to be implied in the book and around the blog that you used more cold air exposure and less ice baths.
I would be most grateful for a brief outline! I.e. 5 min cold shower in morning, 10 min ice bath to waste then 5 mins to neck in evening.
It would be nice if we only lost fat and water when losing “weight”, but unfortunately muscle loss comes along for the ride. I hope you address how to minimize muscle loss while utilizing thermogenesis for fat loss.
Very good point,
Here is one other way to think about it. Just because you eat a protein excess does not mean that your body loses any less.
For example, do the opposites hold true? If you eat just fat, will you lose muscle and glycogen and not fat? if you eat carbs do you lose fat and protein and not glycogen?
I think our generalizations are good to talk about things in a larger sense, but fail miserably when tested against the complexity of biology. The diet industry is probably one of the most egregious offenders.
This is perhaps a better way to look at it – caloric deficit of ALL macronutrients results in your body going to it’s energy backups: fat and glycogen stores.
To put this in perspective, a 120 lb woman at 10% bodyfat would have 12 lbs of fat or 42,000 kcal. If her RMR was at 1500 kcal/day then that’s a 28 day supply of “energy.” Looking at it another way, it is enough energy to run 16 marathons.
Now 10 percent is pretty lean and the numbers scale favorably positive for obese men and women. I just don’t think it is as drastic as all of the draconian dogma we hear about. Do the self-experiment.
I believe we worry about things that aren’t quite true. If you are doing a reasonable amount (not extreme) of exercise and conditioning, your body is smart enough not to use your heart muscle (or any muscle) for fuel.
Perhaps increase muscle loss measured is related to chronic over consumption of protein in general? Perhaps It’s related to unnecessarily excessive exercise using the assumption we need that to “burn fat” when in fact it might be “destroying muscle tissue” at greater rate? I’d like to expand peoples thinking beyond these cut and dry generalizations that obviously aren’t working too well for the population as a whole.
What I know is that for the last three years, I’ve ingested MUCH less protein than any period in my life and I don’t see signs of atrophy.
Thanks for the comment,
Ray
Thanks for the reply.
I have another question about muscle growth. You read it everywhere, “consume 1 g of protein per lb.” Since the concept has been around a long time I find it both suspect and yet comforting in its simplicity.
So, can a plant based diet can provide ALL of the essential (indispensable) amino acids needed for muscle gain when combined with systematic resistance training? And, if so, how much more would need to be consumed?
I’ve been eating a mostly plant based diet for some weeks now and I’ve found the sheer volume of food to be amazing. My jaw muscles have undoubtedly been developing nicely. Now I’m wondering about growing the rest of my musculature when I add resistance to my program.
On another note, I saw both “Fat, Sick and Nearly Dead” and “Forks over Knives” this last week (thanks nflix). I found both enjoyable and eye opening and recommend them. The “foodie” trend towards learning about cuisine and real food in our country is quite heartening and will undoubtedly continue towards a focus on plants.
You should go back and read Part 1 again. There are many things we “read everywhere’ that aren’t true, or worse, true only in very limited cases and then generalized to be always true.
We don’t need protein. we need amino acids. There are 20 total – half of them our body synthesizes and half we must ingest. It really doesn’t matter which “food package” they come in, except that there can be other things (sugars, fats, etc…) that have other impacts. Keep in mind there are MANY other proteins in your body beside muscle tissues. We once believed that there where 100,000 protein-encoding genes, but the Human Genome Project shocked the community and has settled on 19,599 with “2189 DNA segments that are predicted to be to be protein-coding genes” SEE: Human Genome Project.
Why is this important? Because I think the idea we all have fixed in our brain that muscle = protein is a completely flawed construct. This is NOT anti-meat, but pro-science. You need amino acids for the other 19,000 or so proteins in you body. No one is saying for example, so where am I getting my insulin or where will I get my keratin (fingernail/hair protein).
We make proteins – all proteins – one amino acid at a time. If you are amino deficient, muscle tissue is actually a place where the body goes to “scavenge” some more. All proteins are created and eventually consumed as part of an ongoing repair. This is a good video to watch and you can ignore all the fancy words and get the concept. These genes use three base pairs to “code” for each amino acid. It’s run like paper on a player piano to synthesize each and every protein one amino acid at a time.
As for what contains the essential 10 amino acids we can’t synthesize? Potatoes and rice to start, but the list goes wide and deep because plants use all the same amino acids. Some may not be in the same concentration as what is found in animal sources, but excess is excess.
Hope that helps. I wouldn’t sweat protein. It’s not something you NEED to focus on. Eat healthy foods and it will just happen – automagically.
Thanks Ray. I guess after getting into nutrient density I was wondering what elements I may not receive as I’ve been reducing consumption of animal products. In the back of my mind I knew vegsumers need to supplement their diets in one way or another.
After searching I found more info regarding muscle growth and brain function, including the roles (and ratios of) certain long-chain polyunsaturated fats.
The deficiencies one might encounter are well documented for those of us embarking upon this journey. The more I learn about food, the more I realize the less I know. It’s fascinating.
I look forward to learning more from you as well.
Hey, Ray – Just a quick question. I see a theme in what you write: “Calorie Restriction”. Do you have a general rule for the total amount of calories one should consume? ie. 10 kcal per lb of lean body mass, or similar?
Tim
Hey Tim
This has been the focus of the last three months for me. I’ve gained/lost 12 lbs in self experiments. I plan to post on this soon, but wanted to have a good regiment for what works reliably.
It turns out to be actually quite easy, although transition was difficult – mainly in understanding the satiety curve. I now understand both high carb/low carb (forgive me for using the terms – useless, but understood by many) approach and exactly what is going on in terms of energy utilization and weight.
Ray
dude, if you spent half the time posting prescriptive articles (practical recommendations) as you do descriptive articles, you’d have way more readers and you’d actually get the donations you need.
Take a tip from Jack Kruise, give the ppl a protocol to follow, don’t force feed them what you think they should know.
Thanks for the comment. There are many thousand readers and I’m takin the time to blog abou things that interest me – these are areas where I want to challenge status quo. It’s free. I don’t force feed anything – just write.
If you have a question about technical information that will be generally helpful to others, feel free to ask it. Otherwise, you are welcome to email me with comments.
Ray
I love what you do and HOW you do it.
What do you think of the idea that lepicin [?] Modulates the set point of the body and that it makes perminent weight loss unlikely?
Hey Ray,
It’s misleading to characterize glycogen as a protein with a carbohydrate shell. As your diagram shows, it has carbohydrate at the periphery and protein at the center, but the protein part of each glycogen structure is less than 5% of the mass. The protein dimer has a molecular weight of about 74 kD. It’s surrounded by many thousands of glucose molecules, each glucose having a molecular weight of .162 kD (ordinarily 0.18 kD but a water molecule is removed in linking each one to the polymer chain). Since there are thousands (10-30,000) glucose molecules per glycogen structure, each structure is 95.5 to 98.5% carbohydrate. Shouldn’t you call glycogen a ball of tightly packed carbohydrate anchored to a tiny protein core?
Having said that I agree with your statement that it’s silly to conflate protein with meat and dairy.
Thanks for the comment.
Sure, if that were the only sentence I said about it and a person had no other information, I’d go with that. It’s a fuzzy ball of carbohydrate with protein at the core. It can be said either way, but the important thing as pointed out in Carbohydrates Part 3 (where I go into much more detail) is that it is the body’s only way to store a carbohydrate. We primarily store fat and if you do that same calculation of “energy density” we have no more than 2000 calories of glycogen (~500ish in the liver the balance in the muscle) and of course even a 140 lbs, 10% (lean) woman has nearly 25x that many calories in fat (also has proteins in it).
One thing you inadvertently (I assume) stumbled on to is the effect of expressing composition as a % of mass. Scientist do this and It works in the world of biochemistry, but fails in the world of nutrition. If you represent the per calorie percentage (macronutriend/100 calories ingested) then all foods start looking VERY different.
Certainly its “carbohydrate-ness” is more pronounced than it’s “protein-ness” by weight (or calorie). Still my point is actually made, because I am trying to distinguish protein from muscle. I believe that the entire protein, carbohydrate or fat debate is bunk, not that a calorie isn’t a calorie. Certainly digestibility varies as we will see in the next post, but recently I heard a 60+ year old woman at a breakfast bar in a hotel say, “you know I really need some protein this morning.” I can assure you she didn’t need FOOD much less protein. A glass of water would have been just fine.
“Having said that I agree with your statement that it’s silly to conflate protein with meat and dairy.”
well, all right then. You got the point and for that I am grateful.
I understand every word you said above that and could add a few more paragraphs, but it won’t change the core meaning and what any of this has to do with food. That’s the point. It’s taken me months to build a foundation that is based only on what is at the core of energy conversion of food. I am going to rebuild a mental picture of food soon and I will certainly slaughter a sacred cow and slap some agave. What we have risen too is an unitelligable mess and some of the most educated people (yours truly included) have been driveling out pure nonsense when it comes to food and nutrition for decades.
Have you seen protein carbs and fat labels on beer? WTF? when you do the math of course the main calorie is alcohol. Our characterization of food to “help” people has completely failed. I’d like to fix it in the minds of those who will listen.
I think using “protein, carbohydrates and fat” to construct a diet in any way (outside of pure research under controlled conditions) is nearly meaningless. If you don’t own or use a direct/indirect calorimeter they you probably don’t need those words to describe food – doctors, dietitians, and nutritionist included. The reason all diets work are based on caloric restriction – be it portion controlled (what most people think) or metabolic havoc (forcing the system way out of equilibrium); in the end both approaches result with calories (ingested or pushed away) not invited to the love handle party.
Thanks. I hope you go back and read Carbohydrates – 3. I DON’T want to mislead, but it’s always going to be a fuzzy protein in my book to differentiate animal/plant “starch.”
Thanks!
Ray
Went back to read Carbohydrates 3 and yes – you gave a very nice explanation there. As for the comparison by mass above, in this particular case it’s equivalent to a comparison by energy content because protein (the macronutrient) and carbohydrates (the macronutrient) have nearly the same caloric density.
Thanks for the reply – not many bloggers stay interested in discussions all the way down to comment #36.
Regards,
Siobhan
Hi Ray,
I’ve been catching up on several years of your posts. Looking forward to the next ones. You made a comment in this post that sounds like you are currently putting together information on effective ways to cook at home. (Which is fantastic.) In addition, I would welcome similar information for when we are eating out at restaurants.
i.e. Are there any common, inexpensive restaurants that can provide meals within the diet you are moving towards?
Or perhaps tips for analyzing the nutrition information provided by the restaurant? (Check out the salad dressing nutrition before putting it on the salad. Or check to see if veggies are prepared with excessive fat before going to town on a triple portion of them.)
For example:
http://www.chipotle.com/en-us/menu/nutritional_information/nutritional_information.aspx
It looks like I could order a quintuple serving of the fajita veggies to really fill up.
But if I ordered a double salad to fill up, the 2 Vinaigrette dressings it came with would ruin the meal from a caloric standpoint.
And what about the more processed foods. Corn tortilla ok or stay away?
I know we should generally cook at home more and eat out less, but it would be useful to have some backup options for times when we are eating out. Hope you consider it.
Thanks for all the great information,
Ed
[…] loss” particularly urinary nitrogen. As we learned in Passing the Protein (part 1, part 2), urea is the metabolite of amino acid metabolism and so one can track loss by collecting 24 hour […]