We’ve covered a lot of ground. What we’ve discussed is that carbohydrates come in the form of simple sugars (monosaccharides) and more complex carbohydrates (polysaccharides). We know that the sugar names all end in “ose” (glucose, fructose, lactose, etc…). Polysaccharides are many of these monosaccharides linked together in a chain and are a common way plants store energy (similar to our fat) for later use.
I’m suggesting you stop thinking about “Carbs” as a food group; instead categorize meat, vegetables, grains, dairy, etc… Starch (potato) and Cellulose (wood) are made from IDENTICAL glucose molecules. They have a different saccharide bonds, only one of which we have the enzyme (amylase) to digest.
So in Part 3, I want to talk about another pseudo-carbohydrate that is critical for you – glycogen. Many of you are familiar with glycogen from athletics. It’s the “load” part of carb-loading in preparation for a race. It’s also the center of your glucose-centric metabolism and the reason I personally don’t think “carbs” are bad or unhealthy.
What is unhealthy is the way we process high-energy foods with even more empty calories and then consume them in excessive quantities.
So, let’s take a little step back to understand what glycogen is and why it’s important to your performance and your life. Your body has three basic storage points for energy: ATP (adenosine triphosphate), glycogen, and fat. the most immediate energy – what is behind the muscle explosion is ATP. You have about 250 grams of this stuff, about the same amount of energy as is contained in a AA battery, energy comes form popping off one of the phosphates to form ADP (adenosine diphosphate + energy)(1). We then use this other enzyme many of you will be familiar with, creatine kinase, to shuttle these phosphates back and forth.
Save the Liver
ATP is at the very basic level of your energy utilization. Just above this in the “energy food chain,” is our friend, glycogen. Think of glycogen as a “fuzzy protein.” It is made of a core protein, glycogenin, surrounded by fuzzy starch (poly glucose) hairs. It is located throughout your body. You have about 2000 calories at any given time; 500 or so is stored in your liver and the rest packed among your muscles where it can be readily accessed. I’m using approximate numbers because everyone is slightly different, but here is an interesting side fact.
It takes (about) 2600 calories to run a marathon. 2000 calories/2600 calories = 77%. Now using that number and knowing a marathon is 42.2Km/26.2M we see that 77% is 32.5Km/20.2 miles. Anyone that has attempted to run a marathon can tell you about that number: THE WALL. If you are like me and would rather freeze your ass off than run a marathon, that is the point where ATP can no longer be generated by glycogen stores (you’ve run out) and you MUST resort to stored fat.
Fat is then the highest level and quantity of stored energy in your body and the body has to work to get it into a primary glucose-based energy system. Conversely, fatty foods (Oils, lards, etc) have the densest energy reserves. It’s simple: fat is there for long term storage. Plants, and Humans have carbohydrate based reserves for the most immediate needs and that is in your blood sugar level and glycogen reserve.
Record marathoners have trained their bodies to dip into fat reserves much earlier and they use fat throughout the race. When we get back to fat metabolism and thermal loading, you’ll find this is a side benefit of conditioning your body to withstand cold – free fatty acids (FFA) liberated from your fat stores. You may remember from BATGirl, that the mitochondria of BAT and other tissue can use FFA in the presence of a special up-regulating proteins to create HEAT instead of generating ATP.
Your ability to regularly engage in this FFA economy can be significantly influenced by running marathons – extreme milage volume causes this switch as does mild cold stress. People make fun of me about cold all the time, but I just think this is far easier than running 50 miles/day. You may see it different.
What happens in Protein-rich diets is you have depleted your glycogen reserves and it’s energetically costly to refill glycogen from converting protein. Your body switches over to fat metabolism and voilà, you start losing weight. That’s how it works and the ultimate decision one should consider is what will be the long term health effects by using your body’s tertiary macronutrient, protein, to drive it into a secondary reserve, fat, by depleting it from it’s primary energy, glucose. The other direction works just as well and in a glycogen replete state, Chris Voigt lost weight eating 20 potatoes a day – all bad carbs. This is an interesting contrast to the high-fat approach and I think it’s far more important than a silly PR stunt.
Seems complicated, but I just want people to discuss this factually and make informed decisions.
We can equally manage 1) hunger (satiety) and 2) total caloric intake, while maintaining correct micronutrient intake, living permanently thin as opposed to yo-yo dieting. This does require modifications to your lifestyle and I won’t tell you it is trivial, but neither is bypass surgery, insulin shots, high blood pressure, or lugging around an extra 50-200 lbs.
So, there really is not debate that carbohydrate, particularly starch, is a perfectly natural food. As we process with cooking (or over process) ANY carbohydrate, the energy becomes more readily available and then we damn “starch” as the bad-calorie; it’s simply not true. What is interesting is there are many ways to put your body into “survival mode” and only two that have ever demonstrated longevity in laboratory animals: caloric restriction and mild cold stress.
We still have to cover proteins and fats and we’ll keep the rules engaged, neither are food groups. As well, I want you guys to jump in on new commenters in the future and explain when we discuss carbohydrate here, we are primarily discussing high-starch foods that are relatively unprocessed (heated, with no added fat, dairy, or sugar). If you don’t believe me, TRY to go find food in a restaurant that 1) contains a starch and 2) is not loaded with sugar, fat, or dairy. I did it as an experiment for 14 months and know first hand the difficulty.
Brain Drain
We are fat, but let’s not damn potato, squash, and rice – the very staples of Humankind – as the punching bag for of our epidemic obesity. Let’s acknowledge that preparation and added empty calories play the MAJORITY role. When I construct a new paradigm to consider for eating at the end, you’ll see that there is plenty of room for carbohydrate (starchy-foods) on the plate.
Starches are an EXCELLENT food option and contain glucose, the only fuel used by the largest energy consumer of your body: The Brain. When you run low on glucose (and glycogen), gluconeogenesis creates glucose from amino acids by stripping off the nitrogens and using what is left to synthesize glucose. Energy for this is driven through beta-oxidation of FFA. If you have a lot of beta-oxidation is occuring (untreated diabetes or starvation), acetyl-CoA builds up, and is converted to the ketone bodies. That’s the basis of ketosis and why ketones are found in your urine.
The brain-blood barrier is the separation of this distinctly different glucose metabolism from the rest of your body. So, I think is at least it is easily questionable to say carbs are “bad” or even the cause of obesity. At the same time, throwing your body completely into starvation mode, while certainly effective to lose weight, might not be the best long term. Of course we have to consider the implications of caloric restriction too. I just raise the question.
With that is it fair to ask if “carbohydrate” was so bad for you, why did we evolve one of the most advanced, energy-conuming brains of any species to use only a carbohydrate fuel?
Think about it.
(1) “On the prebiotic potential of reduced oxidation state phosphorus: the H-phosphinate–pyruvate system,” David E. Bryant, Katie E. R. Marriott, Stuart A. Macgregor, Colin Kilner, Matthew A. Pasek and Terence P. Kee, Chem. Commun., 2010, 46
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